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Leuprorelin, also known as leuprolide, is a manufactured version of a hormone used to treat prostate cancer, breast cancer, endometriosis, uterine fibroids, for early puberty, or as part of transgender hormone therapy.
A gonadotropin-releasing hormone agonist (GnRH agonist) is a type of medication which affects gonadotropins and sex hormones. [1] They are used for a variety of indications including in fertility medicine and to lower sex hormone levels in the treatment of hormone-sensitive cancers such as prostate cancer and breast cancer, certain gynecological disorders like heavy periods and endometriosis ...
[14] [249] [270] These routes do not have the bioavailability and efficacy issues of oral progesterone, and accordingly, can produce considerable antigonadotropic and other progestogenic effects. [ 14 ] [ 267 ] [ 271 ] Transdermal progesterone is poorly effective, owing to absorption issues.
While delayed gastric emptying is possible with all GLP-1s, including semaglutides like Ozempic, Wegovy, and Rybelsus, the other types do not come with a formal warning. GLP-1s can also impact ...
Chemical castration is castration via anaphrodisiac drugs, whether to reduce libido and sexual activity, to treat cancer, or otherwise.Unlike surgical castration, where the gonads are removed through an incision in the body, [1] chemical castration does not remove organs and is not a form of sterilization.
Vial of Depo-Testosterone, a depot injection of testosterone. A depot injection, also known as a long-acting injectable (LAI), is a term for an injection formulation of a medication which releases slowly over time to permit less frequent administration of a medication.
Exemestane is quickly absorbed from the gut, but undergoes a strong first-pass effect in the liver. Highest blood plasma concentrations are reached after 1.2 hours in breast cancer patients and after 2.9 hours in healthy subjects. Maximal aromatase inhibition occurs after two to three days.
The Obama administration is not acting fast enough, says Dr. Andrew Kolodny, the chief medical officer for Phoenix House, one of the largest addiction treatment operations in the country and one that introduced MAT into a previously abstinence-only model a few years ago. “It’s very frustrating,” he says. “They’ve got to do something.”
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