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It is often a sign of myocardial ischemia, of which coronary insufficiency is a major cause. Other ischemic heart diseases causing ST depression include: Subendocardial ischemia [3] or even infarction. [4] Subendocardial means non full thickness ischemia. In contrast, ST elevation is transmural (or full thickness) ischemia; Non Q-wave ...
The nuclear stress test exhibits a sensitivity of 81% and a specificity ranging from 85 to 95%. [22] To arrive at the patient's post test likelihood of disease, the interpretation of the stress test result necessitates the integration of the patient's pretest likelihood with the test's sensitivity and specificity.
Coronary ischemia, myocardial ischemia, [1] or cardiac ischemia, [2] is a medical term for abnormally reduced blood flow in the coronary circulation through the coronary arteries. [3] Coronary ischemia is linked to heart disease , and heart attacks . [ 4 ]
Duke Treadmill Score is one of the tools for predicting the risk of ischemia or infarction in the heart muscle. [1] The calculation is done based on the information obtained from an exercise test by this formula: [citation needed] [exercise duration by Bruce protocol] - [ 5 × (maximal ST elevation or depression)] - [4 × (treadmill angina index)]
Coronary steal is also the mechanism in most drug-based cardiac stress tests; When a patient is incapable of doing physical activity they are given a vasodilator that produces a "cardiac steal syndrome" as a diagnostic procedure. The test result is positive if the patient's symptoms reappear or if ECG alterations are seen. [citation needed]
Ischemia results in tissue damage in a process known as ischemic cascade. The damage is the result of the build-up of metabolic waste products, inability to maintain cell membranes , mitochondrial damage, and eventual leakage of autolyzing proteolytic enzymes into the cell and surrounding tissues.
Many studies from 2018 and on have found that magnesium status is inversely correlated with high blood pressure, stroke, coronary and ischemic heart disease, atrial fibrillation, heart failure ...
The original definition of cardiac syndrome X also mandated that ischemic changes on exercise (despite normal coronary arteries) were displayed, as shown on cardiac stress tests. [17] The primary cause of microvascular angina is unknown, but factors apparently involved are endothelial dysfunction and reduced flow (perhaps due to spasm) in the ...