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The spinal cord is a long, thin, tubular structure made up of nervous tissue that extends from the medulla oblongata in the lower brainstem to the lumbar region of the vertebral column (backbone) of vertebrate animals. The center of the spinal cord is hollow and contains a structure called the central canal, which contains cerebrospinal fluid.
The apex of the posterior grey column, one of the three grey columns of the spinal cord, is capped by a V-shaped or crescentic mass of translucent, gelatinous neuroglia, termed the substantia gelatinosa of Rolando (or SGR) (or gelatinous substance of posterior horn of spinal cord), which contains both neuroglia cells, and small neurons.
The number of vertebrae in a region can vary but overall the number remains the same. In a human spinal column, there are normally 33 vertebrae. [3] The upper 24 pre-sacral vertebrae are articulating and separated from each other by intervertebral discs, and the lower nine are fused in adults, five in the sacrum and four in the coccyx, or tailbone.
The filum terminale is situated centrally [2] amid the spinal nerve roots of the cauda equina [3] [2] (but is not itself a part of the cauda equina [2]).. The inferior-most spinal nerve, the coccygeal nerve, leaves the spinal cord at the level of the conus medullaris via respective vertebrae through their intervertebral foramina, superior to the filum terminale.
The spinothalamic tract is a nerve tract in the anterolateral system in the spinal cord. [1] This tract is an ascending sensory pathway to the thalamus.From the ventral posterolateral nucleus in the thalamus, sensory information is relayed upward to the somatosensory cortex of the postcentral gyrus.
The conus medullaris (Latin for "medullary cone") or conus terminalis is the tapered, lower end of the spinal cord. It occurs near lumbar vertebral levels 1 (L1) and 2 (L2), occasionally lower. [1] [2] The upper end of the conus medullaris is usually not well defined, however, its corresponding spinal cord segments are usually S1–S5.
The pyramidal tracts include both the corticobulbar tract and the corticospinal tract.These are aggregations of efferent nerve fibers from the upper motor neurons that travel from the cerebral cortex and terminate either in the brainstem (corticobulbar) or spinal cord (corticospinal) and are involved in the control of motor functions of the body.
These axons enter the spinal column and penetrate the grey matter of the dorsal horn, where they synapse on second-order neurons in either the substantia gelatinosa of Rolando or the nucleus proprius. Those neurons project their axon to the anterolateral quadrant of the contralateral half of the spinal cord, where they give the spinothalamic tract.
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