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  2. Cardiac excitation-contraction coupling - Wikipedia

    en.wikipedia.org/wiki/Cardiac_excitation...

    This rate can be altered, however, by nerves that work to either increase heart rate (sympathetic nerves) or decrease it (parasympathetic nerves), as the body's oxygen demands change. Ultimately, muscle contraction revolves around a charged atom (ion) , calcium (Ca 2+ ) , [ 3 ] which is responsible for converting the electrical energy of the ...

  3. Cardiac cycle - Wikipedia

    en.wikipedia.org/wiki/Cardiac_cycle

    In a healthy heart all activities and rests during each individual cardiac cycle, or heartbeat, are initiated and orchestrated by signals of the heart's electrical conduction system, which is the "wiring" of the heart that carries electrical impulses throughout the body of cardiomyocytes, the specialized muscle cells of the heart.

  4. Cardiac action potential - Wikipedia

    en.wikipedia.org/wiki/Cardiac_action_potential

    These calcium ions are responsible for the contraction of the heart. Calcium also activates chloride channels called I to2 , which allow Cl − to enter the cell. Increased calcium concentration in the cell also increases activity of the sodium-calcium exchangers, while increased sodium concentration (from the depolarisation of phase 0 ...

  5. Cardiac conduction system - Wikipedia

    en.wikipedia.org/wiki/Cardiac_conduction_system

    The action potentials of cardiac muscle are unusually sustained. This prevents premature relaxation, maintaining initial contraction until the entire myocardium has had time to depolarize and contract. Absence of tetany. After contracting, the heart must relax to fill up again.

  6. Cardiac physiology - Wikipedia

    en.wikipedia.org/wiki/Cardiac_physiology

    This extended period is critical, since the heart muscle must contract to pump blood effectively and the contraction must follow the electrical events. Without extended refractory periods, premature contractions would occur in the heart and would not be compatible with life. [1] (a) There is long plateau phase due to the influx of calcium ions.

  7. Sinoatrial node - Wikipedia

    en.wikipedia.org/wiki/Sinoatrial_node

    Sinus node dysfunction also known as sick sinus syndrome is a group of irregular heartbeat conditions caused by faulty electrical signals of the heart. When the heart's sinoatrial node is defective, the heart's rhythms become abnormal—typically too slow or exhibiting pauses in its function or a combination, and very rarely faster than normal ...

  8. Diad - Wikipedia

    en.wikipedia.org/wiki/Diad

    The rapid influx of calcium into the cell signals for the cells to contract. When the calcium intake travels through an entire muscle, it will trigger a united muscular contraction. This process is known as excitation-contraction coupling. [2] This contraction pushes blood inside the heart and from the heart to other regions of the body.

  9. Cardiac pacemaker - Wikipedia

    en.wikipedia.org/wiki/Cardiac_pacemaker

    It employs pacemaker cells that produce electrical impulses, known as cardiac action potentials, which control the rate of contraction of the cardiac muscle, that is, the heart rate. In most humans, these cells are concentrated in the sinoatrial (SA) node, the primary pacemaker, which regulates the heart’s sinus rhythm.