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C-C chemokine receptor type 2 (CCR2 or CD192 (cluster of differentiation 192) is a protein that in humans is encoded by the CCR2 gene. [5] CCR2 is a CC chemokine ...
CC chemokine receptors (or beta chemokine receptors) are integral membrane proteins that specifically bind and respond to cytokines of the CC chemokine family. They represent one subfamily of chemokine receptors, a large family of G protein-linked receptors that are known as seven transmembrane (7-TM) proteins since they span the cell membrane seven times.
Chemokine receptors are G protein-coupled receptors containing 7 transmembrane helices [5] that are found predominantly on the surface of leukocytes.Approximately 19 different chemokine receptors have been characterized to date, which share many common structural features.
54199 Ensembl ENSG00000121797 ENSMUSG00000043953 UniProt O00421 O35457 RefSeq (mRNA) NM_001130910 NM_003965 NM_017466 NM_001302376 NM_001302377 RefSeq (protein) NP_001124382 NP_003956 NP_001289305 NP_001289306 NP_059494 Location (UCSC) Chr 3: 46.41 – 46.41 Mb Chr 9: 110.88 – 110.89 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse C-C chemokine receptor-like 2 is a protein that in ...
Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, [4] allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell. Inhibition of CCR2 may have an anti-inflammatory effect. [citation needed]
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6347 20293 Ensembl ENSG00000108691 ENSMUSG00000035352 UniProt P13500 Q62401 RefSeq (mRNA) NM_002982 NM_011331 RefSeq (protein) NP_002973 NP_035461 Location (UCSC) Chr 17: 34.26 – 34.26 Mb Chr 11: 81.99 – 81.99 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemoattractant protein 1 (MCP1) and small ...
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