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The glucose tolerance test was first described in 1923 by Jerome W. Conn. [4]The test was based on the previous work in 1913 by A. T. B. Jacobson in determining that carbohydrate ingestion results in blood glucose fluctuations, [5] and the premise (named the Staub-Traugott Phenomenon after its first observers H. Staub in 1921 and K. Traugott in 1922) that a normal patient fed glucose will ...
The fasting plasma glucose and oral glucose tolerance tests are more sensitive than the A1C test. These tests might pick up prediabetes that may be missed by the A1C test.
A level below 5.6 mmol/L (100 mg/dL) 10–16 hours without eating is normal. 5.6–6 mmol/L (100–109 mg/dL) may indicate prediabetes and oral glucose tolerance test (OGTT) should be offered to high-risk individuals (old people, those with high blood pressure etc.). 6.1–6.9 mmol/L (110–125 mg/dL) means OGTT should be offered even if other ...
In type 1 diabetes, there is a lower total level of insulin to control blood glucose, due to an autoimmune-induced loss of insulin-producing beta cells in the pancreas. [12] [13] Diagnosis of diabetes is by blood tests such as fasting plasma glucose, oral glucose tolerance test, or glycated hemoglobin (A1c). [3]
An oral glucose tolerance test (OGTT) may be normal or mildly abnormal in simple insulin resistance. Often, there are raised glucose levels in the early measurements, reflecting the loss of a postprandial peak (after the meal) in insulin production.
To assist in diagnosis, a doctor may order an HbA1c test, which measures the blood sugar average over the two or three months before the test. The more specific 6-hour glucose tolerance test can be used to chart changes in the patient's blood sugar levels before ingestion of a special glucose drink and at regular intervals during the six hours ...
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