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Folinic acid, under the drug name leucovorin, a form of folate (formyl-THF), can help "rescue" or reverse the toxic effects of methotrexate. [59] Folic acid supplements have little established role in cancer chemotherapy.
Both high-folate diets and supplemental folic acid may help reduce the toxic side-effects of low-dose methotrexate without decreasing its effectiveness. [8] [9] Anyone taking low-dose methotrexate for the health problems listed above should consult with a physician about the need for a folic acid supplement.
Folinic acid, also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate and pyrimethamine. [2] [3] It is also used in combination with 5-fluorouracil to treat colorectal cancer and pancreatic cancer, may be used to treat folate deficiency that results in anemia, and methanol poisoning.
D ietary supplements are a booming ... can take a prenatal vitamin that contains folic acid along with other micronutrients, Manson says. ... safe and doesn't have all these side effects." Not all ...
Folic acid is one supplement that has wide support from public health experts for its proven benefits during pregnancy. (Getty Images) (LWA/Dann Tardif via Getty Images)
Nitric Oxide Supplement Side Effects. ... Folic acid is also commonly added to many breads, cereals, pastas and other grain products in order to prevent nutritional deficiencies.
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