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Since hexane cannot be easily deprotonated, it is used in the laboratory for reactions that involve very strong bases, such as the preparation of organolithiums. For example, butyllithiums are typically supplied as a hexane solution. [10] Hexanes are commonly used in chromatography as a non-polar solvent. Higher alkanes present as impurities in ...
Strongly polar compounds like sugars (e.g. sucrose) or ionic compounds, like inorganic salts (e.g. table salt) dissolve only in very polar solvents like water, while strongly non-polar compounds like oils or waxes dissolve only in very non-polar organic solvents like hexane.
[citation needed] For example, nonpolar hexane is much less viscous than polar water. However, molecule size is a much stronger factor on viscosity than polarity, where compounds with larger molecules are more viscous than compounds with smaller molecules.
In normal-phase chromatography, the least polar compounds elute first and the most polar compounds elute last. The mobile phase consists of a nonpolar solvent such as hexane or heptane mixed with a slightly more polar solvent such as isopropanol, ethyl acetate or chloroform. Retention decreases as the amount of polar solvent in the mobile phase ...
This Wikipedia page provides a comprehensive list of boiling and freezing points for various solvents.
e.g. using hexane, heptane, cyclohexane, or mineral oil as the nonpolar solvent. Nonpolar solvent / polar solvent / salt / water e.g. 100 ml mineral oil, 100 ml isopropanol, 75 ml water, 35 g calcium chloride; Nonpolar solvent / water-soluble polymer A, water-soluble polymer B, water e.g. hexane, polyethylene oxide, dextran, water
For example, water is very polar, and has a relative static permittivity of 80.10 at 20 °C while n-hexane is non-polar, and has a relative static permittivity of 1.89 at 20 °C. [26] This information is important when designing separation, sample preparation and chromatography techniques in analytical chemistry.
Lipophilicity (from Greek λίπος "fat" and φίλος "friendly") is the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene. Such compounds are called lipophilic (translated as "fat-loving" or "fat-liking" [1] [2]). Such non-polar solvents are themselves lipophilic, and the ...