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  2. Mirtazapine - Wikipedia

    en.wikipedia.org/wiki/Mirtazapine

    Mirtazapine is sometimes described as a noradrenergic and specific serotonergic antidepressant (NaSSA), [11] although the actual evidence in support of this label has been regarded as poor. [17] It is a tetracyclic piperazine-azepine. [85] Mirtazapine has antihistamine, α 2-blocker, and antiserotonergic activity.

  3. Noradrenergic and specific serotonergic antidepressant

    en.wikipedia.org/wiki/Noradrenergic_and_specific...

    They act by antagonizing the α 2-adrenergic receptor and certain serotonin receptors such as 5-HT 2A and 5-HT 2C, [1] but also 5-HT 3, [1] 5-HT 6, and/or 5-HT 7 in some cases. By blocking α 2 -adrenergic autoreceptors and heteroreceptors , NaSSAs enhance adrenergic and serotonergic neurotransmission in the brain involved in mood regulation ...

  4. Tetracyclic antidepressant - Wikipedia

    en.wikipedia.org/wiki/Tetracyclic_antidepressant

    Besides mirtazapine, they also block the α 1-adrenergic receptor [citation needed]. Conversely, whereas TCAs have relatively low affinity for the α 2 -adrenergic receptor , mianserin and mirtazapine potently antagonize this receptor, and this action is thought to be involved in their antidepressant effects [ citation needed ] .

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  6. List of psychotropic medications - Wikipedia

    en.wikipedia.org/wiki/List_of_psychotropic...

    Remeron (mirtazapine) – an atypical antidepressant, used off-label as a sleep aid; Restoril – a benzodiazepine used to treat insomnia; Risperdal (risperidone) – atypical antipsychotic used to treat schizophrenia, bipolar disorder and irritability associated with autism; Ritalin (methylphenidate) – a stimulant used to treat ADHD

  7. A review that considered berberine’s effects on heart health found some studies supporting this claim, but due to the high risk of bias, the researchers recommended more clinical trials be ...

  8. 5-HT3 antagonist - Wikipedia

    en.wikipedia.org/wiki/5-HT3_antagonist

    0.25 mg dose Ramosetron: Benzimidazole derivative 5-HT 3 receptor antagonist 5.8 hours 300 μg/kg Tropisetron [30] Indole: 5-HT 3 receptor antagonist 5.6 hours CYP 3A3/4/5, CYP2D6: 200 μg/kg Vortioxetine: Phenylpiperazine: 5-HT 3 receptor antagonist Antidepressant 66h CYP 2D6/ 2A6/CYP2B6/CYP2C8/9, CYP2C19: 5 mg, 10 mg, 20 mg doses

  9. Bright Side (YouTube channel) - Wikipedia

    en.wikipedia.org/wiki/Bright_Side_(YouTube_channel)

    Bright Side (stylized in all caps) is a Cypriot YouTube channel operated by media publisher TheSoul Publishing. Founded in 2017, the channel uploads videos regarding how-to trivia as well as history and knowledge and mistakes. The YouTube channel has over 44.6 million subscribers to its main channel, and over 10.938 billion views. [3]

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