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Pituitary pars intermedia dysfunction (PPID), or equine Cushing's disease, is an endocrine disease affecting the pituitary gland of horses. It is most commonly seen in older animals, [ 1 ] and is classically associated with the formation of a long, wavy coat ( hirsutism ) and chronic laminitis .
Orexin (/ ɒ ˈ r ɛ k s ɪ n /), also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. [5] It exists in the forms of orexin-A and orexin-B.The most common form of narcolepsy, type 1, in which the individual experiences brief losses of muscle tone ("drop attacks" or cataplexy), is caused by a lack of orexin in the brain due to destruction of the cells ...
The endogenous orexin neuropeptides, orexin A and orexin B, are involved in the regulation of sleep–wake cycles and act to promote wakefulness. [33] [16] [7] Deficiency of orexin signaling is thought to be the primary cause of the sleep disorder narcolepsy. [33] [16] Disturbances in orexin signaling may also be involved in insomnia. [33]
Darby Dan Farm is a produce, livestock, and thoroughbred horse breeding and training farm founded in 1935 near the Darby Creek in Galloway, Ohio by businessman John W. Galbreath. [1] Named for the creek and for Galbreath's son, Daniel M. Galbreath (1928–1995), it was expanded from an original 85-acre (340,000 m 2 ) farm into a 4,000 acre (16 ...
The lateral hypothalamus (LH), also called the lateral hypothalamic area (LHA), [1] contains the primary orexinergic nucleus within the hypothalamus that widely projects throughout the nervous system; [2] this system of neurons mediates an array of cognitive and physical processes, such as promoting feeding behavior and arousal, reducing pain perception, and regulating body temperature ...
Orexin, otherwise known as hypocretin, is a neuropeptide that acts within the brain to regulate appetite and wakefulness as well as a number of other cognitive and physiological processes. [27] [38] [39] Loss of these orexin-producing neurons causes narcolepsy and most individuals with narcolepsy have a reduced number of these neurons in their ...
230777 Ensembl ENSG00000121764 ENSMUSG00000028778 UniProt O43613 P58307 RefSeq (mRNA) NM_001525 NM_001163027 NM_198959 NM_001305392 NM_001357258 RefSeq (protein) NP_001516 NP_001156499 NP_001292321 NP_945197 NP_001344187 Location (UCSC) Chr 1: 31.62 – 31.63 Mb Chr 4: 130.02 – 130.03 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Orexin receptor type 1 (Ox1R or OX 1), also known ...
Horses on the Pryor Mountains Wild Horse Range in Montana. The BLM distinguishes between "herd areas" (HA) where feral horse and burro herds existed at the time of the passage of the Wild and Free-Roaming Horses and Burros Act of 1971, and "Herd Management Areas" (HMA) where the land is currently managed for the benefit of horses and burros, though "as a component" of public lands, part of ...
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