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The endometrial biopsy is a medical procedure that involves taking a tissue sample of the lining of the uterus. The tissue subsequently undergoes a histologic evaluation which aids the physician in forming a diagnosis.
It is an uncommon form of endometrial cancer that typically arises in postmenopausal women. It is typically diagnosed on endometrial biopsy, prompted by post-menopausal bleeding. Unlike the more common low-grade endometrioid endometrial adenocarcinoma, uterine serous carcinoma does not develop from endometrial hyperplasia and is not hormone ...
Endometrial hyperplasia is a condition of excessive proliferation of the cells of the endometrium, or inner lining of the uterus. Most cases of endometrial hyperplasia result from high levels of estrogens , combined with insufficient levels of the progesterone-like hormones which ordinarily counteract estrogen's proliferative effects on this ...
The risk of endometrial cancer is reduced by an estimated 30% and the protective effect of hormonal birth control against endometrial cancer increases the longer someone is on it.
Endometrial intraepithelial neoplasia (EIN) is a premalignant lesion of the uterine lining that predisposes to endometrioid endometrial adenocarcinoma. It is composed of a collection of abnormal endometrial cells, arising from the glands that line the uterus , which have a tendency over time to progress to the most common form of uterine cancer ...
The Papanicolaou test (abbreviated as Pap test, also known as Pap smear (AE), [1] cervical smear (BE), cervical screening (BE), [2] or smear test (BE)) is a method of cervical screening used to detect potentially precancerous and cancerous processes in the cervix (opening of the uterus or womb) or, more rarely, anus (in both men and women). [3]
Long-term use of oral contraceptives with highly potent progestins can also induce endometrial atrophy. [ 13 ] [ 14 ] In humans, the cycle of building and shedding the endometrial lining lasts an average of 28 days.
The procedure can also aid in regulation of the menstrual cycle and to obtain a sample for endometrial biopsy. [11] A study found use of Karman vacuum aspiration to be a safer option for endometrial biopsy when compared to the alternatives such as conventional endometrial curettage. [3] It is also used to terminate molar pregnancy. [12]