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Rifampicin can be used as monotherapy for a few days as prophylaxis against meningitis, but resistance develops quickly during long-term treatment of active infections, so the drug is always used against active infections in combination with other antibiotics.
Of the first-line drugs, rifampicin is also the most expensive, and in the poorest countries, regimens omitting rifampicin are therefore often used. Rifampicin is the most potent sterilising drug available for the treatment of tuberculosis and all treatment regimens that omit rifampicin are significantly longer than the standard regimen.
Lepetit introduced Rifampicin, an orally active rifamycin, in 1966. [16] Rifabutin, a derivative of rifamycin S, was invented by Italian drug manufacturer Achifar in 1975 and came onto the US market in 1992. [16] Hoechst Marion Roussel (now part of Aventis) introduced rifapentine to the US market in 1998, with Achifar having synthesized it in ...
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USP 800 (Hazardous Drugs—Handling in Healthcare Settings) is a guideline created by the United States Pharmacopeia Convention (USP), as one of their General Chapters through which the USP "sets quality standards for medicines, dietary supplements and food ingredients".
Medication waste from this source can be from over prescribing of drugs from healthcare providers, hospital labs, expired drugs, opened drug containers and partially used medications. [5] Furthermore, these wastes can include materials, such as syringes, vials, IV bags, and tubing that contain excess drugs or contaminated in the process of ...
Still, for general implementation of drug recycling programs, clear professional guidelines are required. [2] Research could provide the rationale for these guidelines. For example, research showed that a majority of patients is willing to use recycled drugs if the quality is maintained, [ 13 ] and explored requirements for a drug recycling ...