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There are three common naming conventions for specifying one of the two enantiomers (the absolute configuration) of a given chiral molecule: the R/S system is based on the geometry of the molecule; the (+)- and (−)- system (also written using the obsolete equivalents d- and l-) is based on its optical rotation properties; and the D/L system is based on the molecule's relationship to ...
In chemistry, a racemic mixture or racemate (/ r eɪ ˈ s iː m eɪ t, r ə-, ˈ r æ s ɪ m eɪ t / [1]) is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule or salt. Racemic mixtures are rare in nature, but many compounds are produced industrially as racemates.
As indicated earlier, the (R)- enantiomer is the pharmacologically active diuretic. Like most other diuretics, the (R)-isomer possesses an undesirable side-effect of retaining uric acid. But the (S)-enantiomer, the distomer , has the property of assisting uric acid secretion (uricosuric effect), and, therefore, antagonizing the undesirable side ...
6-Br-APB is a synthetic compound that acts as a selective D 1 agonist, [1] with the (R)-enantiomer being a potent full agonist, while the (S) enantiomer retains its D 1 selectivity but is a weak partial agonist. [2]
Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, [10] [12] is the S(+) enantiomer of ketamine. [5] [13] It is a dissociative hallucinogen drug used as a general anesthetic and as an antidepressant for treatment of depression.
Arketamine (developmental code names PCN-101, HR-071603), also known as (R)-ketamine or (R)-(−)-ketamine, is the (R)-(−) enantiomer of ketamine. [1] [2] [3] Similarly to racemic ketamine and esketamine, the S(+) enantiomer of ketamine, arketamine is biologically active; however, it is less potent as an NMDA receptor antagonist and anesthetic and thus has never been approved or marketed for ...
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Limonene is a chiral molecule, and biological sources produce one enantiomer: the principal industrial source, citrus fruit, contains (+)-limonene (d-limonene), which is the -enantiomer. [ 1 ] (+)-Limonene is obtained commercially from citrus fruits through two primary methods: centrifugal separation or steam distillation .
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