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Tamsulosin – ARISTO Pharma – 0.4 mg prolonged-release tablets – Urologikum. Tamsulosin, sold under the brand name Flomax among others, is a medication used to treat symptomatic benign prostatic hyperplasia (BPH) and chronic prostatitis and to help with the passage of kidney stones.
The risk of first dose phenomenon may be reduced or eliminated by gradual-dose titration, since the adverse effects of Prazosin are dose-related. [7] This is also the case for Tamsulosin and it may be assumed that the others alpha-1 blockers work in a similar manner, since Tamsulosin is an alpha-1-a blocker and Prazosin is an alpha-1 blocker. [30]
For men with LUTS due to an enlarged prostate, the effects of naftopidil, tamsulosin and silodosin on urinary symptoms and quality of life may be similar. [58] Naftopidil and tamsulosin may have similar levels of unwanted sexual side effects but fewer unwanted side effects than silodosin. [58]
One of the most common side effects with alpha blockers is the first dose effect. [29] This is a phenomenon in which patients with hypertension take an alpha blocker for the first time, and suddenly experience an intense decrease in blood pressure.
The effectiveness of alpha blockers (tamsulosin, alfuzosin) is questionable in men with CPPS and may increase side effects like dizziness and low blood pressure. [64] A 2006 meta-analysis found that they are moderately beneficial when the duration of therapy was at least three months.
In elderly men, for instance, tadalafil has a slightly longer half-life of roughly 21.6 hours. As a long-lasting ED medication, tadalafil is only recommended for use one time per day.
Age: Older people may have degeneration of neural pathways involved with bladder function and it can lead to an increased risk of postoperative urinary retention. [6] The risk of postoperative urinary retention increases up to 2.11 fold for people older than 60 years. [6]
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