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Symptoms depend on the type of thalassemia and can vary from none to severe, including death. [1] Often there is mild to severe anemia (low red blood cells or hemoglobin) as thalassemia can affect the production of red blood cells and also affect how long the red blood cells live. [1] Symptoms of anemia include feeling tired and having pale ...
Severe symptoms include liver cirrhosis, liver fibrosis, and in extreme cases, liver cancer. [10] Heart failure, growth impairment, diabetes and osteoporosis are life-threatening conditions which can be caused by beta thalassemia major. [11]
Splenic sequestration crisis is a life-threatening illness common in pediatric patients with homozygous sickle cell disease and beta thalassemia.Up to 30% of these children may develop splenic sequestration crisis with a mortality rate of up to 15%.
Anemia experienced by some thalassemia intermedia patients are also regarded transfusion dependent. Therefore, most transfusion-dependent thalassemia patients can be diagnosed within the first few years of life, which severe anemia, differed growth, jaundice and hepatosplenomegaly can be observed. Parameters for confirmation includes baseline ...
It has numerous possible consequences, ranging from general symptoms to life-threatening systemic effects. [2] The general classification of hemolytic anemia is either intrinsic or extrinsic. [3] Treatment depends on the type and cause of the hemolytic anemia. [2]
The other is the fact that the first sign may be a life-threatening allergic reaction known as anaphylaxis (think: throat-swelling, difficulty breathing) in people who develop the condition, often ...
In the first months of life, fetal hemoglobin disappears and the amount of hemoglobin E increases, so the subjects start to have a mild β-thalassemia. Subjects homozygous for the hemoglobin E allele (two abnormal alleles) have a mild hemolytic anemia and mild enlargement of the spleen .
Food poisoning symptoms can vary widely in severity, as can the length of time one feels sick. Many people feel better after several hours, but it is not uncommon for symptoms to persist for 24 to ...