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  2. Free-radical halogenation - Wikipedia

    en.wikipedia.org/wiki/Free-radical_halogenation

    For example, consider radical bromination of toluene: [5] bromination of toluene with hydrobromic acid and hydrogen peroxide in water. This reaction takes place on water instead of an organic solvent and the bromine is obtained from oxidation of hydrobromic acid with hydrogen peroxide. An incandescent light bulb suffices to radicalize.

  3. Halogen addition reaction - Wikipedia

    en.wikipedia.org/wiki/Halogen_addition_reaction

    A halogen addition reaction is a simple organic reaction where a halogen molecule is added to the carbon–carbon double bond of an alkene functional group. [1] The general chemical formula of the halogen addition reaction is: C=C + X 2 → X−C−C−X (X represents the halogens bromine or chlorine, and in this case, a solvent could be CH 2 ...

  4. Photochlorination - Wikipedia

    en.wikipedia.org/wiki/Photochlorination

    Reaction scheme of the photobromination of the methyl group of toluene Photobromination with elemental bromine proceeds analogous to photochlorination also via a radical mechanism. In the presence of oxygen, the hydrogen bromide formed is partly oxidised back to bromine, resulting in an increased yield.

  5. Halogenation - Wikipedia

    en.wikipedia.org/wiki/Halogenation

    Illustrative of the bromination of an alkene is the route to the anesthetic halothane from trichloroethylene: [6] Iodination and bromination can be effected by the addition of iodine and bromine to alkenes. The reaction, which conveniently proceeds with the discharge of the color of I 2 and Br 2, is the basis of the analytical method.

  6. Benzyl bromide - Wikipedia

    en.wikipedia.org/wiki/Benzyl_bromide

    Benzyl bromide is used in organic synthesis for the introduction of the benzyl groups when the less expensive benzyl chloride is insufficiently reactive. [6] [7] Benzylations are often achieved in the presence of catalytic amounts of sodium iodide, which generates the more reactive benzyl iodide in situ. [3]

  7. Electrophilic halogenation - Wikipedia

    en.wikipedia.org/wiki/Electrophilic_halogenation

    Halogenation of benzene where X is the halogen, catalyst represents the catalyst (if needed) and HX represents the protonated base. A few types of aromatic compounds, such as phenol , will react without a catalyst , but for typical benzene derivatives with less reactive substrates, a Lewis acid is required as a catalyst .

  8. Haloform reaction - Wikipedia

    en.wikipedia.org/wiki/Haloform_reaction

    In chemistry, the haloform reaction (also referred to as the Lieben haloform reaction) is a chemical reaction in which a haloform (CHX 3, where X is a halogen) is produced by the exhaustive halogenation of an acetyl group (R−C(=O)CH 3, where R can be either a hydrogen atom, an alkyl or an aryl group), in the presence of a base.

  9. Hell–Volhard–Zelinsky halogenation - Wikipedia

    en.wikipedia.org/wiki/Hell–Volhard–Zelinsky...

    The reaction is initiated by addition of a catalytic amount of PBr 3, after which one molar equivalent of Br 2 is added. PBr 3 converts the carboxylic OH to the acyl bromide. The acyl bromide tautomerizes to an enol, which reacts with the Br 2 to brominate at the α position.In neutral to slightly acidic aqueous solution, hydrolysis of the α-bromo acyl bromide occurs spontaneously, yielding ...