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  2. Upadacitinib - Wikipedia

    en.wikipedia.org/wiki/Upadacitinib

    Upadacitinib was approved in January 2022, by the FDA for treating adults and children twelve years of age and older with moderate to severe treatment refractory atopic dermatitis. [ 10 ] [ 17 ] Upadacitinib was approved in March 2022, by the FDA for treating adults with moderately to severely active ulcerative colitis who did not respond to ...

  3. FDA Approves AbbVie's JAK Inhibitor Application For Active ...

    www.aol.com/news/fda-approves-abbvies-jak...

    The FDA approved AbbVie Inc's (NYSE: ABBV) Rinvoq (upadacitinib; 15 mg) for active psoriatic arthritis (PsA). Like Pfizer Inc's (NYSE: PFE) approval for Xeljanz, Rinvoq's approval also covers ...

  4. FDA Approves AbbVie's Upadacitinib For Refractory Atopic ...

    www.aol.com/news/fda-approves-abbvies...

    The FDA has approved AbbVie Inc's (NYSE: ABBV) Rinvoq (upadacitinib) for atopic dermatitis in adults and children 12 years of age and older. The approval covers moderate to severe atopic ...

  5. AbbVie's JAK Inhibitor Rinvoq Receives Approval for RA in EU

    www.aol.com/news/abbvies-jak-inhibitor-rinvoq...

    AbbVie's (ABBV) oral JAK inhibitor, upadacitinib, receives approval in Europe for treating rheumatoid arthritis under the trade name of Rinvoq.

  6. Filgotinib - Wikipedia

    en.wikipedia.org/wiki/Filgotinib

    Filgotinib is a Janus kinase inhibitor with selectivity for subtype JAK1 of this enzyme. It is considered a promising agent as it inhibits JAK1 selectively, similar to already marketed upadacitinib.

  7. Tofacitinib - Wikipedia

    en.wikipedia.org/wiki/Tofacitinib

    The FDA approved only the five-mg, twice-daily dose on the grounds that a higher dose was not considered to have an adequate risk-to-benefit ratio. [ 34 ] In September 2020, the FDA approved tofacitinib for the treatment of children and adolescents two years of age and older with active polyarticular course juvenile idiopathic arthritis.

  8. 19 drug approvals in 2024 that had 'big clinical impact ... - AOL

    www.aol.com/19-drug-approvals-2024-had-093022917...

    GoodRx released a list of 19 of the most influential drugs and vaccines approved by the FDA in 2024 to treat a variety of conditions. These medications are “slated to make a big clinical impact."

  9. Psoriatic arthritis - Wikipedia

    en.wikipedia.org/wiki/Psoriatic_arthritis

    The JAK1 inhibitors tofacitinib (Xeljanz) and upadacitinib (Rinvoq) are approved for the use in active psoriatic arthritis. [34] The TYK2 inhibitor deucravacitinib (Sotyktu), which has been approved for plaque psoriasis, is currently undergoing a Phase II clinical trial to evaluate the efficacy and safety on psoriatic arthritis.