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Optic nerve melanocytoma does not usually produce symptoms or grow. If they slowly grow, optic nerve melanocytoma can produce afferent pupillary defects (30%), subretinal fluid (10%), and an enlarged blind spot (75%). On fundoscopic exam, the optic disc may be swollen, atrophic, or even normal. [1] Central retinal vein occlusion may occur.
The actual number of meningiomas is likely much higher as it is very common in elderly women [citation needed]. ONSM comprises about 2% of orbital tumors, and about 10% of optic nerve lesions. [8] Neurofibromatosis type II (NF-2) affects around 9% of ONSM patients, where the incidence in the general population is around 0.03–0.05%. Thus NF-2 ...
Coloboma of optic nerve is a rare defect of the optic nerve that causes moderate to severe visual field defects. Coloboma of the optic nerve is a congenital anomaly of the optic disc in which there is a defect of the inferior aspect of the optic nerve. The issue stems from incomplete closure of the embryonic fissure while in utero.
Ocular disc dysplasia is the most notable ocular defect of the disease. An abnormal development in the optic stalk causes optic disc dysplasia, which is caused by a mutation in the Pax2 gene. [4] The nerve head typically resembles the morning glory disc anomaly, but has also been described as a coloboma. [4]
Peripheral nerve tumors [5] [2] Tumor type Malignancy Estimated incidence Location Schwannoma Benign 1.09 per 100,000/year Skin and subcutaneous tissues of the head and neck, or along the flexor surfaces of the extremities; Spinal intradural extramedullary site with growth into foraminal space; Eight cranial nerve (bilateral involvement in NF2)
NAION is believed to be caused by reduced blood flow to the optic nerve head. It can lead to permanent visual loss in one eye that may develop painlessly and suddenly or over several days before ...
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Optic gliomas are usually pilocytic tumors, and can involve the optic nerve or optic chiasm. [3] Optic gliomas are usually associated with neurofibromatosis type 1 in 30% of people with the condition. [3] Optic nerve gliomas have low mortality but extremely high prevalence of vision loss and eye-bulging exophthalmos) in children. [4]