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Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis. [9] [10] It can be given orally (by mouth), intramuscularly (injection into a muscle), or intravenously ...
Ondansetron is a racemate but the stereochemistry of the asymmetric carbon atom is not an important factor in the 5-HT 3 receptor interaction. Annelation of the 1,7-positions of the indole nucleus of ondansetron results in increased affinity for the receptor .
“Zofran is an anti-nausea medication,” says Qing, and it’s typically used preventatively. Zofran is an antiemetic that works by blocking the chemical that causes nausea and vomiting, per the ...
Positron emission tomography (PET) studies, have demonstrated that aprepitant can cross the blood brain barrier and bind to NK 1 receptors in the human brain. [10] It has also been shown to increase the activity of the 5-HT 3 receptor antagonist ondansetron and the corticosteroid dexamethasone , which are also used to prevent nausea and ...
Here's what doctors thing is behind personality changes caused by Ozempic and other GLP-1s and what you can do about it.
The following are settlements reached with US authorities against pharmaceutical companies to resolve allegations of "off-label" promotion of drugs. Under the Federal Food, Drug, and Cosmetic Act, it is illegal for pharmaceutical companies to promote their products for uses not approved by the Food and Drug Administration (FDA), and corporations that market drugs for off-label indications may ...
It’s tamale time. This Mexican comfort food has a long history and is an essential part of every major holiday, particularly Christmas. It’s also the perfect portable snack for holiday travelers.
Long-term nuclear waste warning messages are communication attempts intended to deter human intrusion at nuclear waste repositories in the far future, within or above the order of magnitude of 10,000 years. Nuclear semiotics is an interdisciplinary field of research, first established by the American Human Interference Task Force in 1981.
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