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An urban legend suggests that tetryzoline can cause violent diarrhea if given orally, such as by putting a few drops of Visine in an unsuspecting person's beverage. However, the actual results of the prank may be worse, varying from severe nausea and vomiting to seizures or a coma.
The FDA recently cautioned against using dozens of kinds of eyedrops — its third warning this year — leading to some wondering whether any drops are safe to use. Eye doctors weigh in.
A debunked urban legend claims that a few drops of Visine will cause harmless but debilitating bouts of explosive diarrhea, similar to a laxative. [14] However, symptoms of Visine's active ingredient tetrahydrozoline hydrochloride can be severe, and can include: Dangerously low body temperature (hypothermia) Blurred vision; Nausea and vomiting
While many different things can cause diarrhea—including infections or a more serious gastrointestinal condition—in most cases, it will go away after a few days without the need for treatment.
Effects of anticholinergic drugs include: Delirium (often with hallucinations and delusions indistinguishable from reality) Ocular symptoms (from eye drops): mydriasis, pupil dilation, and acute angle-closure glaucoma in those with shallow anterior chamber [11] [12] [13] Anhidrosis, dry mouth, dry skin; Fever; Constipation; Tachycardia; Urinary ...
The Food and Drug Administration compiled a list of over-the-counter eye drops to avoid. 27 eye drops from retailers in California can cause vision loss, FDA warns. See the recall
The most important factor that must be taken into account when designing any type of drug delivery device, and specifically ocular devices, is the release rate of a drug. As discussed previously, the deliver rate and kinetics associated with drugs to the eye can reach levels that are toxic to the eye or could even cause undesirable side effects.
The CDC warned that EzriCare Artificial Tears eyedrops may be linked to a drug-resistant bacterial infection that has caused permanent vision loss and one death.