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Fatty acids change how genes work. The researchers found that both propionate and butyrate altered gene expression in several isolated human cell types: healthy cells and treated colon cancer cells.
Past studies show that an imbalanced gut microbiome may lead to health issues such as inflammatory bowel disease (IBD), type 2 diabetes, cardiovascular disease, and depression.
The nutrient has been shown to help guard against breast cancer, while a diet rich in vitamin A has been linked to a lower risk for squamous cell carcinoma, a common form of skin cancer.
Apart from butyrate, F. prausnitzii produce formate and D-lactate as byproducts of fermentation of glucose and acetate. [13] [7] Lower than usual levels of F. prausnitzii in the intestines have been associated with Crohn's disease, obesity, asthma and major depressive disorder.
Advertisement suggesting that a healthy diet helps prevent cancer. Many dietary recommendations have been proposed to reduce the risk of cancer, few have significant supporting scientific evidence. [1] [2] [3] Obesity and drinking alcohol have been correlated with the incidence and progression of some cancers. [1]
Butyrate fermentation is a process that produces butyric acid via anaerobic bacteria. This process occurs commonly in clostridia which can be isolated from many anaerobic environments such as mud, fermented foods , and intestinal tracts or feces. [ 1 ]
Nutrition and diet are closely associated with the leading causes of death, including cardiovascular disease and cancer. Obesity and high sodium intake can contribute to ischemic heart disease, while consumption of fruits and vegetables can decrease the risk of developing cancer. [99]
Corresponding author Shria Kumar, MD, MSCE, gastroenterologist and clinical epidemiologist at the Sylvester Comprehensive Cancer Center, explained the findings of this new study to Medical News Today.