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Grey matter undergoes development and growth throughout childhood and adolescence. [3] Recent studies using cross-sectional neuroimaging have shown that by around the age of 8 the volume of grey matter begins to decrease. [4] However, the density of grey matter appears to increase as a child develops into early adulthood. [4]
Synaptic pruning, a phase in the development of the nervous system, is the process of synapse elimination that occurs between early childhood and the onset of puberty in many mammals, including humans. [1] Pruning starts near the time of birth and continues into the late-20s. [2]
Cortical white matter increases from childhood (~9 years) to adolescence (~14 years), most notably in the frontal and parietal cortices. [8] Cortical grey matter development peaks at ~12 years of age in the frontal and parietal cortices, and 14–16 years in the temporal lobes (with the superior temporal cortex being last to mature), peaking at about roughly the same age in both sexes ...
Grey matter has also been shown to positively correlate with intelligence in children. [ 27 ] [ 28 ] [ 29 ] Reis and colleagues [ 29 ] have found that grey matter in the prefrontal cortex contributes most robustly to variance in Intelligence in children between 5 and 17, while subcortical grey matter is related to intelligence to a lesser extent.
Total cerebral and gray matter volumes peak during the ages from 10–20 years (earlier in girls than boys), whereas white matter and ventricular volumes increase. There is a general pattern in neural development of childhood peaks followed by adolescent declines (e.g. synaptic pruning). Consistent with adult findings, average cerebral volume ...
MRI of a child experiencing seizures.There are small foci of grey matter heterotopia in the corpus callosum, deep to the dysplastic cortex. (double arrows) Gray matter heterotopia is a neurological disorder caused by gray matter being located in an atypical location in the brain.
Image credits: Chance_Ad4487 #5. Around four or five months ago, at like 3:00am I was awoken by a very weird growling sound. Disoriented and in the dark I started to come to and for the life of me ...
Pachygyria is a condition identified by a type of cortical genetic malformation. Clinicians will subjectively determine the malformation based on the degree of malposition and the extent of thickened abnormal grey differentiation present. [2]