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The BNF for Children developed from the British National Formulary (BNF), which prior to 2005 had provided information on the treatment of children, with the doses largely determined by calculations based on the body weight of the child. The guidance was provided by pharmacists and doctors whose expertise was in the care of adults.
The British National Formulary for Children (BNFC) [1] [19] [20] book, first published September 2005, [2] is published yearly, [2] and details the doses and uses of medicines in children from neonates to adolescents. [1]
A formulary is a list of pharmaceutical drugs, often decided upon by a group of people, for various reasons such as insurance coverage or use at a medical facility. [1] Traditionally, a formulary contained a collection of formulas for the compounding and testing of medication (a resource closer to what would be referred to as a pharmacopoeia ...
Urea in low doses is a humectant while at high doses (above 20%) it causes breakdown of protein in the skin. [ 9 ] Urea dissolves the intercellular matrix of the cells of the stratum corneum , promoting desquamation of scaly skin , eventually resulting in softening of hyperkeratotic areas. [ 5 ]
Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...
[23] [13] First made in 1977, [20] ketoconazole was the first orally-active azole antifungal medication. [23] However, ketoconazole has largely been replaced as a first-line systemic antifungal medication by other azole antifungal agents, such as fluconazole and/or itraconazole , because of ketoconazole's greater toxicity, poorer absorption ...
The formula is used in therapeutic feeding centers where children are hospitalized for treatment. [1] F-75 is considered the "starter" formula, and F-100 the "catch-up" formula. [ 2 ] The designations mean that the product contains respectively 75 and 100 kcals per 100 ml. F-75 provides 75 kcal and 0.9 g protein per 100 mL, while F-100 provides ...
Use is thus not recommended in children less than two years old. [2] It comes in a number of different strengths. [3] Salicylic acid overdose can lead metabolic acidosis with compensatory respiratory alkalosis. In people presenting with an acute overdose, a 16% morbidity rate and a 1% mortality rate are observed. [10]
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