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Diablo homolog (DIABLO) is a mitochondrial protein that in humans is encoded by the DIABLO (direct IAP binding protein with low pI) gene on chromosome 12. [5] [6] [7] DIABLO is also referred to as second mitochondria-derived activator of caspases or SMAC. This protein binds inhibitor of apoptosis proteins (IAPs), thus freeing caspases to ...
Swedish snaplock gun from the early 16th century. The origin of this proto-flintlock is unclear. The earliest source which could be speaking of a snaplock is an account from 1515 where a young man in Konstanz, Germany accidentally shot a girl with a pistol, thinking it could not go off due to the lack of a lit match.
A snaphance or snaphaunce is a type of firearm lock in which a flint struck against a striker plate above a steel pan ignites the priming powder which fires the gun. [1] It is the mechanical progression of the wheellock firing mechanism, and along with the miquelet lock and doglock are predecessors of the flintlock mechanism .
Diablo II sold 4 million copies in the year it was released. Diablo III sold 3.5 million copies in the first day and 6.3 million copies in the first week. [76] Another 1.2 million copies were given to subscribers to Blizzard's Annual Pass service. The Diablo III release was the fastest-selling PC game of all time. [77]
The best way to reheat steak to lock in the flavor and juices? Sous vide. “Sous vide is probably the best way to reheat steak, as it reheats the meat slowly in its own juices,” Edwards says.
A man who tortured a man for two days before he jumped to his death from a 12th-storey flat has been jailed for eight years. Lee Smith, 37, abducted Jamie Forbes, also 37, and held him against his ...
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