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1q21.1 duplication syndrome arises from microduplications of the BP3-BP4 region, containing at least seven genes and a minimum duplicated region of ~1.2 Mb of unique DNA sequence. [ 7 ] 1q21.1 duplication syndrome has an autosomal dominant inheritance pattern, where 18–50% of deletions happen de novo and 50–82% are inherited from their parents.
On the other side, autism is significantly more common with 1q21.1 duplication syndrome. Further research confirmed that the odds on a relation between schizophrenia and deletions at 1q21.1, 3q29 , 15q13.3, 22q11.21 en Neurexin 1 (NRXN1) and duplications at 16p11.2 are at 7.5% or higher.
From 2000 to 2019, Google frequently inserted jokes and hoaxes into its products on April Fools' Day, which takes place on April 1.The company ceased performing April Fools jokes in 2020 due to the COVID-19 pandemic and has not performed them since.
Middlemost Post is an American animated comedy television series created by John Trabbic III and developed by Dave H. Johnson and Trabbic III for Nickelodeon.It aired from July 9, 2021, to October 21, 2022.