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It is important for patients to eat 3 meals a day as well in order to reduce the chances of hypoglycemia, especially with patients that take insulin. [ 1 ] There is a lack of evidence of the usefulness of low-carbohydrate dieting for people with type 1 diabetes (T1D). [ 20 ]
In rare instances, metformin may lead to low blood sugar levels (hypoglycemia). This may happen if you’re not eating enough food, are drinking alcohol, or are taking other medications to lower ...
Although it must be used with caution in patients with impaired liver or kidney function, Metformin, a biguanide, has become the most commonly used agent for type 2 diabetes in children and teenagers. Among common diabetic drugs, Metformin is the only widely used oral drug that does not cause weight gain. [9]
Gastrointestinal upset can cause severe discomfort; it is most common when metformin is first administered, or when the dose is increased. [76] [81] The discomfort can often be avoided by beginning at a low dose (1.0 to 1.7 g/day) and increasing the dose gradually, but even with low doses, 5% of people may be unable to tolerate metformin.
Another meta-analysis of 33 studies involving 61,704 patients found that compared with non-metformin control groups, metformin usage among people with pre-existing cardiovascular conditions is ...
When diabetes is the cause, physicians typically recommend an anti-diabetic medication as treatment. From the perspective of the majority of patients, treatment with an old, well-understood diabetes drug such as metformin will be the safest, most effective, least expensive, most comfortable route to managing the condition. [ 7 ]
The complications of diabetes can dramatically impair quality of life and cause long-lasting disability. Overall, complications are far less common and less severe in people with well-controlled blood sugar levels. [3] [4] [5] Some non-modifiable risk factors such as age at diabetes onset, type of diabetes, gender, and genetics may influence risk.
[100] [101] Hypoglycemia is associated with adverse outcomes in older people with type 2 diabetes. [102] Despite guidelines recommending that intensive blood sugar control be based on balancing immediate harms with long-term benefits, many people – for example people with a life expectancy of less than nine years who will not benefit, are ...
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