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Posaconazole, sold under the brand name Noxafil among others, is a triazole antifungal medication. [ 7 ] [ 8 ] It was approved for medical use in the European Union in October 2005, [ 6 ] and in the United States in September 2006.
After oral or intravenous administration, isavuconazonium is rapidly hydrolysed by esterases in blood or the gastrointestinal tract to the active form, isavuconazole. [7] [8] [15] Isavuconazole works by inhibition of lanosterol 14α-demethylase, the enzyme responsible for converting lanosterol to ergosterol by demethylation.
Scedosporiosis is the general name for any mycosis – i.e., fungal infection – caused by a fungus from the genus Scedosporium.Current population-based studies suggest Scedosporium prolificans (also known and recently more commonly referred to as Lomentospora prolificans) and Scedosporium apiospermum to be among the most common infecting agents from the genus, [1] although infections caused ...
An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cryptococcal meningitis, and others.
Aspergillus 235 mags 3X3 copy. Aspergillosis is caused by Aspergillus, a common mold, which tends to affect people who already have a lung disease such as cystic fibrosis or asthma, or who cannot fight infection themselves. [3] The most common causative species is Aspergillus fumigatus. [19]
Aspergillus (/ ˌ æ s p ər ˈ dʒ ɪ l ə s /) is a genus consisting of several hundred mold species found in various climates worldwide. Aspergillus was first catalogued in 1729 by the Italian priest and biologist Pier Antonio Micheli .
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Itraconazole has a broader spectrum of activity than fluconazole (but not as broad as voriconazole or posaconazole). In particular, it is active against Aspergillus, which fluconazole is not. It is also licensed for use in blastomycosis, sporotrichosis, histoplasmosis, and onychomycosis.
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