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The lowest pH of the secreted acid is 0.8, [7] but the acid is diluted in the stomach lumen to a pH of between 1 and 3. There is a small continuous basal secretion of gastric acid between meals of usually less than 10 mEq/hour. [8] There are three phases in the secretion of gastric acid which increase the secretion rate in order to digest a ...
In gastroenterology, esophageal pH monitoring is the current gold standard for diagnosis of gastroesophageal reflux disease (GERD). It provides direct physiologic measurement of acid in the esophagus and is the most objective method to document reflux disease, assess the severity of the disease and monitor the response of the disease to medical or surgical treatment.
Hyperchlorhydria, sometimes called chlorhydria, sour stomach or acid stomach, [1] [2] refers to the state in the stomach where gastric acid levels are higher than the reference range. The combining forms of the name ( chlor- + hydr- ), referring to chlorine and hydrogen , are the same as those in the name of hydrochloric acid , which is the ...
After leaving the stomach, the hydrochloric acid of the chyme is neutralized in the duodenum by bicarbonate. [36] The stomach itself is protected from the strong acid by the secretion of a thick mucus layer, and by secretin induced buffering with sodium bicarbonate. Heartburn or peptic ulcers can develop when these mechanisms fail.
Acid reflux, or gastroesophageal reflux (GERD), is a common condition that happens when stomach acid flows back up into the esophagus, causing discomfort such as heartburn. It can be triggered by ...
When an acid is dissolved in water, the pH will be less than 7, while a base, or alkali, will have a pH greater than 7. A strong acid, such as hydrochloric acid, at concentration 1 mol dm −3 has a pH of 0, while a strong alkali like sodium hydroxide, at the same concentration, has a pH of 14. Since pH is a logarithmic scale, a difference of ...
Acid reflux, a condition in which stomach acids and contents can return to the esophagus, causing irritation, burping, and burning pain, is an aspect of gastroesophageal reflux disease (GERD).
A fourth phase of acid secretion is known as the basal state which occurs in the times between meals (interdigestive phase). The level of acid secretion during these times is regulated by body weight, individual, number of parietal cells, and time of day. Acid secretion is lowest in the morning before awakening and highest at night. [2]
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