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Pre-gestational diabetes can be classified as Type 1 or Type 2 depending on the physiological mechanism. Type 1 diabetes mellitus is an autoimmune disorder leading to destruction of insulin-producing cell in the pancreas; type 2 diabetes mellitus is associated with obesity and results from a combination of insulin resistance and insufficient insulin production.
Gestational diabetes is formally defined as "any degree of glucose intolerance with onset or first recognition during pregnancy". [4] This definition acknowledges the possibility that a woman may have previously undiagnosed diabetes mellitus, or may have developed diabetes coincidentally with pregnancy.
Thus a lowering of disposition index predicts the conversion of insulin resistance to diabetes mellitus type 2. [13] Disposition index, but not insulin resistance, can predict type 2 diabetes in persons with normal blood glucose levels, but who do not have a family history ( genetic predisposition ) to type 2 diabetes.
Multiple pieces of evidence show those with double diabetes mellitus have increased risks for complications from the condition in the future. [1] Furthermore, some people with double diabetes can reverse the type 2 version of their diabetes or the involved insulin resistance but the type 1 is permanent; the latter cannot be reversed. [2] [3]
Type 3 diabetes is a proposed pathological linkage between Alzheimer's disease and certain features of type 1 and type 2 diabetes. [1] Specifically, the term refers to a set of common biochemical and metabolic features seen in the brain in Alzheimer's disease, and in other tissues in diabetes; [1] [2] it may thus be considered a "brain-specific type of diabetes."
Detective Kat Donovan continues to be haunted by the murder of her father, a police officer, and the ghosting by her fiancé, Josh, 11 years earlier.
Horizon: An American Saga is a film series of four planned American epic westerns.It is directed, co-written, produced by, and starring Kevin Costner, from a script he co-wrote with Jon Baird and based on an original story co-written by Costner, Baird, and Mark Kasdan.
Rosamund Mary Ellen Pike [2] (born 1979) [a] is an English actress and producer. Known for her portrayals of morally ambiguous women in psychological thrillers and dramas, she is the recipient of numerous accolades, including a Primetime Emmy Award and a Golden Globe Award, as well as nominations for an Academy Award and two BAFTA Awards.