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Goodpasture syndrome (GPS), also known as anti–glomerular basement membrane disease, is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs, glomerulonephritis, [1] and kidney failure. [2]
Goodpasture syndrome: Kidneys, lungs: Anti-GBM antibodies Confirmed 1 per million people [46] IgA nephropathy: Kidneys: IgA autoantibodies Confirmed 3.5 per 100,000 [47] Membranous nephropathy: Kidneys: Anti-PLA2R antibodies Confirmed 10 per 100,000 [48] Lupus nephritis: Kidneys: Anti-dsDNA, Anti-Sm, Anti-nuclear antibodies Confirmed Up to 60% ...
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Anti-glomerular basement membrane antibody (anti-GBM Ab) is an antibody which is found in Goodpasture's syndrome but not found in microscopic polyangiitis.. Some sources consider "anti-GBM disease" and "Goodpasture disease" to be synonymous terms describing histological presentation, reserving the term "Goodpasture syndrome" for clinical presentation.
This syndrome caused every subsequent generation in a bloodline to have their life expectancy shortened. When the amber lead concentration in the body is fatally high, white blotches appear on the victim's skin, their hair becomes white, and they feel intense chronic pain. The only known survivor of this syndrome is Trafalgar D. Water Law.
Goodpasture syndrome; Gordon syndrome; Gougerot–Blum syndrome; Gourmand syndrome; Gouverneur's syndrome; GRACILE syndrome; Graham-Little syndrome; Gray baby syndrome; Gray platelet syndrome; Greater trochanteric pain syndrome; Green nail syndrome; Greig cephalopolysyndactyly syndrome; Grinspan's syndrome; Griscelli syndrome type 2; Griscelli ...
Pulmonary-renal syndrome (PRS) is a rare medical syndrome in which respiratory failure involving bleeding in the lungs and kidney failure (glomerulonephritis) occur. [1] PRS is associated with a high rate of morbidity and death. [1] The term was first used by Goodpasture in 1919 to describe the association of respiratory and kidney failure. [1]
1285 12828 Ensembl ENSG00000169031 ENSMUSG00000079465 UniProt Q01955 Q9QZS0 RefSeq (mRNA) NM_000091 NM_031362 NM_031363 NM_031364 NM_031365 NM_031366 NM_007734 RefSeq (protein) NP_000082 NP_031760 Location (UCSC) Chr 2: 227.16 – 227.31 Mb Chr 1: 82.56 – 82.7 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Collagen alpha-3(IV) chain is a protein that in humans is encoded by the ...