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A New Pain Medication Could Reinforce the Disastrous Crackdown on Prescription Opioids. Jacob Sullum. January 30, 2024 at 1:25 PM. K-State/Flickr.
Suzetrigine (developmental code name VX-548) is a non-opioid, small-molecule analgesic that works as a selective inhibitor of Na v 1.8-dependent pain-signaling pathways in the peripheral nervous system. [1] [2] It is being developed by Vertex Pharmaceuticals and has completed two phase 3 clinical trials. [1] [3]
Drugs granted breakthrough therapy designation (BTD) by the US Food and Drug Administration (FDA). Drugs may be listed more than once since breakthrough therapy can be awarded for multiple indications.
Cardiac valvular disease, pulmonary hypertension, cardiac fibrosis; [3] [23] re-approved in June 2020 for the treatment of seizures associated with Dravet syndrome, under FDA orphan drug rules. Fenoterol: 1990 New Zealand Asthma mortality. [3] Feprazone: 1984 Germany, UK Cutaneous reaction, multiorgan toxicity. [3] Fipexide: 1991 France ...
Zohydro was approved for treating chronic pain, but the coalition is concerned about the drug's potency and abuse potential,' WWLP reports. A petition on Change.org calls Zohydro "the next OxyContin."
Before Leqembi was approved, another similar medication was approved called Aduhelm. But while Aduhelm clearly removed Alzheimer’s plaques, Medicare wasn’t convinced that it really helped ...
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