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The Kosambi mapping function was introduced to account for the impact played by crossover interference on recombination frequency. It introduces a parameter C, representing the coefficient of coincidence, and sets it equal to 2r. For loci which are strongly linked, interference is strong; otherwise, interference decreases towards zero. [5]
In genetics, the coefficient of coincidence (c.o.c.) is a measure of interference in the formation of chromosomal crossovers during meiosis. It is generally the case that, if there is a crossover at one spot on a chromosome, this decreases the likelihood of a crossover in a nearby spot. [1] This is called interference.
Crossover interference is the term used to refer to the non-random placement of crossovers with respect to each other during meiosis.The term is attributed to Hermann Joseph Muller, who observed that one crossover "interferes with the coincident occurrence of another crossing over in the same pair of chromosomes, and I have accordingly termed this phenomenon ‘interference’."
Journal of Experimental Pharmacology; Journal of Healthcare Leadership; Journal of Hepatocellular Carcinoma; Journal of Inflammation Research; Journal of Multidisciplinary Healthcare; Journal of Neurorestoratology † Journal of Pain Research; Journal of Receptor, Ligand and Channel Research † Journal of Parkinsonism and Restless Legs Syndrome
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This is a list of journals published by Nature Research. These include the flagship Nature journal, the Nature Reviews series (which absorbed the former Nature Clinical Practice series in 2009), the npj series, Scientific Reports and many others.