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Left ventricular hypertrophy with secondary repolarization abnormalities as seen on ECG Histopathology of (a) normal myocardium and (b) myocardial hypertrophy. Scale bar indicates 50 μm. Gross pathology of left ventricular hypertrophy. Left ventricle is at right in image, serially sectioned from apex to near base.
Ventricular hypertrophy causes a dynamic pressure gradient across the left ventricular outflow tract (LVOT), which is associated with further narrowing of the outflow during systole. Pulling of the mitral valve leaflets towards the septum contributes to the outflow obstruction.
Ventricular hypertrophy (VH) is thickening of the walls of a ventricle (lower chamber) of the heart. [1] [better source needed] Although left ventricular hypertrophy (LVH) is more common, right ventricular hypertrophy (RVH), as well as concurrent hypertrophy of both ventricles can also occur.
In this condition, the walls of the left and/or right ventricles of the heart become thin and stretched. [29] In the other types, the heart's left ventricle becomes abnormally thick. Hypertrophy is usually what causes left ventricular enlargement. Hypertrophic cardiomyopathy is typically an inherited condition. [30]
Ventricular remodeling may include ventricular hypertrophy, ventricular dilation, cardiomegaly, and other changes. It is an aspect of cardiomyopathy, of which there are many types. Concentric hypertrophy is due to pressure overload, while eccentric hypertrophy is due to volume overload. [6]
As blood regurgitates into the left ventricle between each systole, volume overload ensues and the ventricular wall hypertrophies in an attempt to maintain cardiac output and blood pressure. The massive ventricle can lead to a heart weighing over 1000 grams (the weight of a normal heart is about 350 grams), referred to as cor bovinum (Latin for ...
EKG depiction of left ventricular hypertrophy. Left ventricular hypertrophy is a leading cause of sudden cardiac deaths in the adult population. [39] [30] This is most commonly the result of longstanding high blood pressure, or hypertension, which has led to maladaptive overgrowth of muscular tissue of the left ventricle, the heart's main ...
In the absence of heart failure, hypertension, with or without enlargement of the heart (left ventricular hypertrophy) is usually symptomless. [citation needed] Symptoms, signs and consequences of congestive heart failure can include: Fatigue; Irregular pulse or palpitations; Swelling of feet and ankles; Weight gain; Nausea; Shortness of breath
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