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  2. Esketamine - Wikipedia

    en.wikipedia.org/wiki/Esketamine

    Esketamine is the second drug to be approved for TRD by the FDA, following olanzapine/fluoxetine (Symbyax) in 2009. [25] [50] Other agents, like the atypical antipsychotics aripiprazole (Abilify) and quetiapine (Seroquel), have been approved for use in the adjunctive therapy of MDD in people with a partial response to treatment. [25]

  3. Sofosbuvir/velpatasvir - Wikipedia

    en.wikipedia.org/wiki/Sofosbuvir/velpatasvir

    Sofosbuvir/velpatasvir, sold under the brand name Epclusa among others, is a fixed-dose combination medication for the treatment of hepatitis C in adults. [ 2 ] [ 5 ] [ 6 ] [ 7 ] It combines sofosbuvir and velpatasvir .

  4. Velpatasvir - Wikipedia

    en.wikipedia.org/wiki/Velpatasvir

    Velpatasvir reaches highest blood plasma levels three hours after oral intake together with sofosbuvir. Plasma protein binding is over 99.5%. It is slowly metabolised by the liver enzymes CYP2B6, CYP2C8 and CYP3A4.

  5. What You Need to Know About Esketamine, the First Nasal ... - AOL

    www.aol.com/news/know-esketamine-first-nasal...

    For starters, you can’t take it home. For premium support please call: 800-290-4726 more ways to reach us

  6. 19 drug approvals in 2024 that had 'big clinical impact ... - AOL

    www.aol.com/news/19-drug-approvals-2024-had...

    GoodRx released a list of 19 of the most influential drugs and vaccines approved by the FDA in 2024 to treat a variety of conditions. These medications are “slated to make a big clinical impact."

  7. XW10508 - Wikipedia

    en.wikipedia.org/wiki/XW10508

    The drug is a novel esketamine analogue and conjugate that acts as a prodrug of esketamine. [3] Esketamine, and by extension XW10508, is an NMDA receptor antagonist and indirect AMPA receptor activator. [1] [5] XW10508 is being developed as once-daily orally administered extended-release and immediate-release formulations with misuse resistance ...

  8. Does Medicare Cover Ketamine Infusions? - AOL

    www.aol.com/does-medicare-cover-ketamine...

    Although the FDA has approved ketamine for use as an anesthetic, infusion therapy hasn't been approved to treat chronic pain, depression, or other conditions. Skip to main content. Subscriptions ...

  9. Ketamine - Wikipedia

    en.wikipedia.org/wiki/Ketamine

    An enantiomer of ketamine – esketamine commercially sold as Spravato – was approved as an antidepressant by the European Medicines Agency in 2019. [63] Esketamine was approved as a nasal spray for treatment-resistant depression in the United States [64] and elsewhere in 2019 (see Esketamine and Depression). The Canadian Network for Mood and ...