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  2. Telomere - Wikipedia

    en.wikipedia.org/wiki/Telomere

    Telomeres form large loop structures called telomere loops, or T-loops. Here, the single-stranded DNA curls around in a long circle, stabilized by telomere-binding proteins. [26] At the very end of the T-loop, the single-stranded telomere DNA is held onto a region of double-stranded DNA by the telomere strand disrupting the double-helical DNA ...

  3. Telomere-binding protein - Wikipedia

    en.wikipedia.org/wiki/Telomere-binding_protein

    Telomere-binding proteins can generate a T-loop to protect chromosome ends. [2] TRFs are double-stranded proteins which are known to induce bending, looping, and pairing of DNA which aids in the formation of T-loops. They directly bind to TTAGGG repeat sequence in the DNA. [3] There are also subtelomeric regions present for regulation.

  4. Shelterin - Wikipedia

    en.wikipedia.org/wiki/Shelterin

    Shelterin (also called telosome) is a protein complex known to protect telomeres in many eukaryotes from DNA repair mechanisms, as well as to regulate telomerase activity. In mammals and other vertebrates, telomeric DNA consists of repeating double-stranded 5'-TTAGGG-3' (G-strand) sequences (2-15 kilobases in humans) along with the 3'-AATCCC-5' (C-strand) complement, ending with a 50-400 ...

  5. Best Cyber Monday DNA test deals for humans and pets - AOL

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    These are the best deals live as of Nov. 28:BEST HUMAN DNA KIT DEAL: AncestryDNA Genetic Ethnicity Test — $59 $99 (save $40)BEST PET DNA KIT DEAL: Embark Dog DNA Test — $139 $199 (save $60)DNA ...

  6. Flow-FISH - Wikipedia

    en.wikipedia.org/wiki/Flow-FISH

    Flow-FISH was first published in 1998 by Rufer et al. [11] as a modification of another technique for analyzing telomere length, Q-FISH, that employs peptide nucleic acid probes [12] of a 3'-CCCTAACCCTAACCCTAA-5' sequence labeled with a fluorescin fluorophore to stain telomeric repeats on prepared metaphase spreads of cells that have been treated with colcemid, hypotonic shock, and fixation to ...

  7. Commercial animal cloning - Wikipedia

    en.wikipedia.org/wiki/Commercial_animal_cloning

    The first commercially cloned pet was a cat named Little Nicky, produced in 2004 by Genetic Savings & Clone for a north Texas woman for the fee of US$50,000. [24] On May 21, 2008, BioArts International [ 25 ] announced a limited commercial dog cloning service (through a program it called Best Friends Again) in partnership with a Korean company ...

  8. Alternative Lengthening of Telomeres - Wikipedia

    en.wikipedia.org/wiki/Alternative_lengthening_of...

    The main alternative lengthening mechanism for telomeres is a type of homologous recombination called Break-induced Telomere Synthesis (or BITS). [1] Normally, homologous recombination allows broken DNA strands to be repaired by lining up with a matching sequence of undamaged DNA, but in BITS, this mechanism is used to extend telomeres.

  9. Psst...The AncestryDNA Test Kit Is Less than $40 for Amazon ...

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    And great news: The company's genetic test kit, is currently more than half off during Amazon Prime Day 2024 (which runs from today, July 16, through Wednesday, July 17). That's right: The ...

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