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  2. Sequence homology - Wikipedia

    en.wikipedia.org/wiki/Sequence_homology

    Top: An ancestral gene duplication produces two paralogs (histone H1.1 and 1.2). A speciation event produces orthologs in the two daughter species (human and chimpanzee). Bottom: in a separate species , a gene has a similar function (histone-like nucleoid-structuring protein) but has a separate evolutionary origin and so is an analog.

  3. Homology (biology) - Wikipedia

    en.wikipedia.org/wiki/Homology_(biology)

    The term "ortholog" was coined in 1970 by the molecular evolutionist Walter Fitch. [41] Homologous sequences are paralogous if they were created by a duplication event within the genome. For gene duplication events, if a gene in an organism is duplicated, the two copies are paralogous. They can shape the structure of whole genomes and thus ...

  4. Gene family - Wikipedia

    en.wikipedia.org/wiki/Gene_family

    Top: An ancestral gene duplication produces two paralogs (histone H1.1 and 1.2). A speciation event produces orthologs in the two daughter species (human and chimpanzee). Bottom: in a separate species , a gene has a similar function (histone-like nucleoid-structuring protein) but has a separate evolutionary origin and so is an analog.

  5. EVA1C - Wikipedia

    en.wikipedia.org/wiki/EVA1C

    The paralogs of EVA1C are EVA1A (Eva-1 Homolog A) and EVA1B (Eva-1 Homolog B). [17] [18] The thorny skate (Amblyraja radiata) was found to be the most distant ortholog in EVA1A, EVA1B, and EVA1C. [14] [19] [20] The divergence time of humans and the thorny skate is 464 million years ago. [16]

  6. Synteny - Wikipedia

    en.wikipedia.org/wiki/Synteny

    In Hyphomicrobiales and Enterobacteriales, syntenic genes encode a large number of essential cell functions and represent a high level of functional relationships. [ 15 ] Patterns of shared synteny or synteny breaks can also be used as characters to infer the phylogenetic relationships among several species, and even to infer the genome ...

  7. HomoloGene - Wikipedia

    en.wikipedia.org/wiki/HomoloGene

    And then it calculates the statistical significance of each match. Cutoffs are made per position and Ks values are set to prevent false "orthologs" from being grouped together. “Paralogs” are identified by finding sequences that are closer within species than other species. This resource ceased making updates in 2014. [2]

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  9. STAU1 - Wikipedia

    en.wikipedia.org/wiki/STAU1

    Double-stranded RNA-binding protein Staufen homolog 1 is a protein that in humans is encoded by the STAU1 gene. [5] [6] [7]Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles.