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Anti-sp100 antibodies are found in association with primary biliary cirrhosis. [1] The autoimmune target of anti-sp100 is the sp100 nuclear antigen which was identified by its association with primary biliary cirrhosis . 20-30% of patients with primary biliary cirrhosis have sp100 Abs.
Sp100 nuclear antigen is an interferon stimulated antigen found in the cell nuclei of many human and higher animal cells. Autoantibodies directed against Sp100 are often found in patients with primary biliary cirrhosis. [1] Histologically Sp100 'dots' regions of the cell nucleus. Viral infection and mitogens affect the expression of the Sp100 ...
The antigens are either from cell extracts or recombinant. Blood serum is incubated in the wells of the plate and is washed out. If antibodies that bind to antigen are present then they will remain after washing. A secondary anti-human antibody conjugated to an enzyme such as horseradish peroxidase is added. The enzyme reaction will produce a ...
A Texas foster mother is facing serious criminal charges after the teenaged girl in her care died weighing just 78 lbs. while the woman cashed the child’s disability checks.
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Craigslist headquarters in the Inner Sunset District of San Francisco prior to 2010. The site serves more than 20 billion [17] page views per month, putting it in 72nd place overall among websites worldwide and 11th place overall among websites in the United States (per Alexa.com on June 28, 2016), with more than 49.4 million unique monthly visitors in the United States alone (per Compete.com ...
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Texas Lt. Gov. Dan Patrick said U.S.-owned border wall materials, which were available for sale, were pulled from an Arizona auction at the government's request. The Lonestar State had shown ...