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  2. Zonisamide - Wikipedia

    en.wikipedia.org/wiki/Zonisamide

    Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The precise mechanism by which zonisamide exerts its antiseizure effect is unknown, although it is believed that the drug blocks sodium and T-type calcium channels , which leads to the suppression of neuronal hypersynchronization ...

  3. Is It Safe to Use Expired Vitamins? The Truth About Vitamin ...

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    If they’re stored in optimal conditions, you can get the most bang for your buck. Best case scenario, the average shelf-life of vitamins is two years, Davis-Cadogan adds.

  4. Bupropion/zonisamide - Wikipedia

    en.wikipedia.org/wiki/Bupropion/zonisamide

    Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity. [1] [2] [3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker ...

  5. Brinzolamide - Wikipedia

    en.wikipedia.org/wiki/Brinzolamide

    While definitive sites of metabolism have not been firmly established, there are several metabolites worthy of note. N-Desethylbrinzolamide is an active metabolite of the parent compound, and thus exhibits carbonic anhydrase inhibitory activity (largely carbonic anhydrase-I, when in the presence of Brinzolamide) and also accumulates in the erythrocytes.

  6. Ethosuximide - Wikipedia

    en.wikipedia.org/wiki/Ethosuximide

    Ethosuximide, sold under the brand name Zarontin among others, is a medication used to treat absence seizures. [4] It may be used by itself or with other antiseizure medications such as valproic acid. [4]

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  8. Today’s NYT ‘Strands’ Hints, Spangram and Answers for Friday ...

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    Hint: The first one can be found in the top-half of the board. Here are the first two letters for each word: FO. FE. EV. LO. MI. AL (SPANGRAM) NYT Strands Spangram Answer Today.

  9. Doctors Say This Viral "Sleep Rule" Actually Works - AOL

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    “You can think of it as similar to what you do for oral hygiene, such as brushing your teeth and flossing.” How to follow the 10-3-2-1-0 sleep rule 10 hours before bed: No more caffeine

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