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In medicine, salpingo-oophorectomy is the removal of an ovary and its fallopian tube. [1] [2] This procedure is most frequently associated with prophylactic surgery in response to the discovery of a BRCA mutation, particularly those of the normally tumor suppressing BRCA1 gene (or, with a statistically lower negative impact, those of the tumour suppressing BRCA2 gene), which can increase the ...
Prophylactic risk-reducing salpingo-oophorectomy (RRSO) is an important option for the high-risk population to consider. Women with BRCA1/2 mutations who undergo salpingo-oophorectomy have lower all-cause mortality rates than women in the same population who do not undergo this procedure.
If a BSO is combined with an abdominal hysterectomy (there are different methods of hysterectomy available), the procedure is commonly called a TAH-BSO: total abdominal hysterectomy with a bilateral salpingo-oophorectomy. Sexual intercourse remains possible after salpingectomy, surgical and radiological cancer treatments, and chemotherapy.
Currently, the only intervention proven to reduce ovarian cancer risk is bilateral salpingo-oophorectomy (BSO) at age 35–40 for BRCA1 carriers or age 40–45 for BRCA2, which has been shown to decrease incidence by 80-96%. During BSO both ovaries and both fallopian tubes are removed in one operation.
Hysterectomy is the surgical removal of the uterus and cervix.Supracervical hysterectomy refers to removal of the uterus while the cervix is spared. These procedures may also involve removal of the ovaries (oophorectomy), fallopian tubes (salpingectomy), and other surrounding structures.
Oophorectomy when done alongside salpingectomy as a bilateral salpingo-oophorectomy, [17] or alongside hysterectomy or all together, have shown to significant decrease instances of ovarian cancer if the individual has a known history of BRCA1 or BRCA2 mutations and if they have an identified genetic risk of breast and ovarian cancer.
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The term "adnexectomy" in gynaecology is often used for salpingo-oophorectomy (removal of both: fallopian tubes and ovaries). Additional images. Ovary. See also