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  2. A New Pain Medication Could Reinforce the Disastrous ... - AOL

    www.aol.com/news/pain-medication-could-reinforce...

    Vertex Pharmaceuticals is trumpeting the results of clinical trials indicating that VX-548, its new, non-opioid analgesic, is effective at relieving post-surgical pain. While there is nothing ...

  3. Vertex Pharma scientist talks about the long road to ... - AOL

    www.aol.com/lifestyle/vertex-pharma-scientist...

    Vertex Pharmaceuticals recently reported positive results for a non-opioid painkiller, one of several medications the Boston-based drugmaker has been developing for various forms of pain. Patients ...

  4. Vertex's non-opioid drug reduces nerve pain in trial ... - AOL

    www.aol.com/news/vertexs-non-opioid-drug-reduces...

    On the scale, which ranges from 0 for no pain to 10 for worst pain imaginable, patients treated with the drug showed reductions of 2.26, 2.11 and 2.18 at the high, mid and low doses, respectively.

  5. Stephen Waxman - Wikipedia

    en.wikipedia.org/wiki/Stephen_Waxman

    Waxman's next major studies – carried out at a time when the opiate epidemic was causing deaths around the country – helped to propel the search for new, non-addictive pain medications. Every person who has gone to the dentist knows that, after local injection of a medication like novocain, there is no pain.

  6. Metamizole - Wikipedia

    en.wikipedia.org/wiki/Metamizole

    While metamizole is a relatively safe medication, [24] it is not entirely devoid of adverse effects. [24] Metamizole has a potential of blood-related toxicity (blood dyscrasias), but causes less kidney, cardiovascular, and gastrointestinal toxicity than non-steroidal anti-inflammatory drugs (NSAIDs). [11]

  7. Hyoscyamine - Wikipedia

    en.wikipedia.org/wiki/Hyoscyamine

    Hyoscyamine (also known as daturine or duboisine) is a naturally occurring tropane alkaloid and plant toxin. It is a secondary metabolite found in certain plants of the family Solanaceae, including henbane, mandrake, angel's trumpets, jimsonweed, the sorcerers' tree, and Atropa belladonna (deadly nightshade).

  8. 20 innovative breakthroughs that will transform your health - AOL

    www.aol.com/finance/20-innovative-breakthroughs...

    A non-opioid pain medicine. ... the need for non-addictive pain medicine is plain. ... The first new schizophrenia drug in decades. For the past 70 years, antipsychotic medications have been the ...

  9. NFEPP - Wikipedia

    en.wikipedia.org/wiki/NFEPP

    As a result, NFEPP has the potential to reduce opioid addiction and dependency, as there is no effect on users who are not actually suffering from pain, as the chemical does not interact with non-inflamed brain tissue until much higher doses are reached.