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Airway resistance is not constant. As shown above airway resistance is markedly affected by changes in the diameter of the airways. Therefore, diseases affecting the respiratory tract can increase airway resistance. Airway resistance can also change over time. During an asthma attack the airways constrict causing an increase in airway resistance.
Obstructive conditions of the lower airway, including severe asthma or COPD episodes, can also lead to respiratory arrest. During these episodes, known as exacerbations, airway resistance is increased due to inflammatory changes in the lungs. This leads to increased work of breathing and decreased oxygen delivery to tissue.
Dynamic compression of the airways results when intrapleural pressure equals or exceeds alveolar pressure, which causes dynamic collapsing of the lung airways. It is termed dynamic given the transpulmonary pressure (alveolar pressure − intrapleural pressure) varies based on factors including lung volume, compliance, resistance, existing pathologies, etc. [1]
On the other hand, only peak inspiratory pressure increases (plateau pressure unchanged) when airway resistance increases (e.g. airway compression, bronchospasm, mucous plug, kinked tube, secretions, foreign body). [5] Compliance decreases in the following cases: Supine position; Laparoscopic surgical interventions; Severe restrictive pathologies
Dynamic airway compression occurs when intrapleural pressure equals or exceeds alveolar pressure, which causes dynamic collapsing of the lung airways. It is termed dynamic given the transpulmonary pressure (alveolar pressure − intrapleural pressure) varies based on factors including lung volume, compliance, resistance, existing pathologies, etc. [6] It occurs during forced expiration when ...
[citation needed] These medications decrease immune system activity which in turn will decrease swelling of the airways, decrease airway resistance, and increase delivery of air to the alveoli during respiration. Unlike the SABAs, these medications do not provide relief of acute symptoms or asthmatic attacks, and their benefits are typically ...
Peak inspiratory pressure increases with any airway resistance. Factors that may increase P IP include increased secretions, bronchospasm, biting down on ventilation tubing, and decreased lung compliance.
The peak expiratory flow (PEF), also called peak expiratory flow rate (PEFR) and peak flow measurement, [1] is a person's maximum speed of expiration, as measured with a peak flow meter, a small, hand-held device used to monitor a person's ability to breathe out air.