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2. List of 5α-reductase inhibitors - Wikipedia

   en.wikipedia.org/wiki/List_of_5α-reductase...

   This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase.This enzyme is responsible for the conversion of the androgen hormone testosterone into the more potent dihydrotestosterone (DHT) and is essential for the production of neurosteroids like allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from ...

3. Saw palmetto extract - Wikipedia

   en.wikipedia.org/wiki/Saw_palmetto_extract

   Saw palmetto extract has been studied in clinical trials as a possible treatment for people with prostate cancer and for men with lower urinary tract symptoms associated with BPH. [1] [3] As of 2023, there is insufficient scientific evidence that saw palmetto extract is effective for treating cancer or BPH and its symptoms.

4. 5α-Reductase inhibitor - Wikipedia

   en.wikipedia.org/wiki/5α-reductase_inhibitor

   Thus, inhibition results in decreased amounts of DHT. Because of this, slight elevations in testosterone and estradiol levels occur. [36] The 5α-reductase reaction is a rate-limiting step in the testosterone reduction and involves the binding of NADPH to the enzyme followed by the substrate. [4] [37] Substrate + NADPH + H + → 5α-substrate ...

5. Can Finasteride Lower Testosterone? (& Other Potential Side ...

   www.aol.com/finasteride-lower-testosterone-other...

   Saw palmetto is used for a variety of conditions, and hair loss is one of them. Just like finasteride, saw palmetto is a 5-alpha-reductase blocker. You can find saw palmetto in hair-thickening ...

6. How Effective Is Saw Palmetto as a Hair Loss Treatment? - AOL

   www.aol.com/effective-saw-palmetto-hair-loss...

   A plant extract often found in hair loss supplements and shampoo for thinning hair (including DHT-blocking shampoos), saw palmetto extract may be an effective hair loss treatment. ... Side Effects ...

7. Antiandrogen - Wikipedia

   en.wikipedia.org/wiki/Antiandrogen

   As another example, the steroidal antiandrogens cyproterone acetate and spironolactone possess off-target actions including progestogenic, antimineralocorticoid, and/or glucocorticoid activity in addition to their antiandrogen activity, and these off-target activities can result in additional side effects.