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  2. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    Cialis has an impressively long half-life — one dose can last up to 36 hours (hence, its nickname “the weekend pill”). But you can also take Cialis daily at a lower dose if you’re the ...

  3. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Cialis (tadalafil) has a half-life of 17.5 hours, meaning this drug lasts up to 36 hours after it’s consumed. Levitra (vardenafil) ...

  4. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

    www.aol.com/tadalafil-ultimate-guide-dosages...

    In elderly men, for instance, tadalafil has a slightly longer half-life of roughly 21.6 hours. As a long-lasting ED medication, tadalafil is only recommended for use one time per day.

  5. Tadalafil - Wikipedia

    en.wikipedia.org/wiki/Tadalafil

    20 mg Cialis tablet. Tadalafil is used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. [8] In the US, tadalafil (as Cialis) is indicated for the treatment of erectile dysfunction and the signs and symptoms of benign prostatic hyperplasia; [5] and (as Adcirca) for the treatment of pulmonary arterial hypertension to improve exercise ability.

  6. Biological half-life - Wikipedia

    en.wikipedia.org/wiki/Biological_half-life

    So, for example, digoxin has a half-life (or t ⁠ 1 / 2 ⁠) of 24–36 h; this means that a change in the dose will take the best part of a week to take full effect. For this reason, drugs with a long half-life (e.g., amiodarone , elimination t ⁠ 1 / 2 ⁠ of about 58 days) are usually started with a loading dose to achieve their desired ...

  7. Icos - Wikipedia

    en.wikipedia.org/wiki/Icos

    Cialis advertisements were described as being gentler, warmer and with a more relaxed feel than those of its rivals, to reflect the longer duration of the drug. [26] (Tadalafil has a half-life of 17.5 hours, compared to 3.5 for sildenafil and 4.5 for vardenafil.) Iconic themes in Cialis advertisements include couples in bathtubs and the slogan ...

  8. 4 Common ED Pills: Weighing the Pros & Cons of Each - AOL

    www.aol.com/4-common-ed-pills-weighing-141800609...

    Tadalafil has a half-life of 17.5 hours — it remains active in your body for far longer than other ED medications. A single dose of tadalafil can improve blood flow to your privates and make it ...

  9. Clearance (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Clearance_(pharmacology)

    But is also equivalent to ⁡ divided by elimination rate half-life /, = ⁡ /. Thus, C l t o t = ln ⁡ 2 ⋅ V d t 1 / 2 {\displaystyle Cl_{tot}={\dfrac {\ln 2\cdot V_{d}}{t_{1/2}}}} . This means, for example, that an increase in total clearance results in a decrease in elimination rate half-life, provided distribution volume is constant.

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