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A nucleated red blood cell (NRBC), also known by several other names, is a red blood cell that contains a cell nucleus. Almost all vertebrate organisms have hemoglobin -containing cells in their blood, and with the exception of mammals , all of these red blood cells are nucleated. [ 1 ]
Codocytes, also known as target cells, are red blood cells that have the appearance of a shooting target with a bullseye. In optical microscopy these cells appear to have a dark center (a central, hemoglobinized area) surrounded by a white ring (an area of relative pallor), followed by dark outer (peripheral) second ring containing a band of ...
Red blood cells (RBCs), referred to as erythrocytes (from Ancient Greek erythros 'red' and kytos 'hollow vessel', with -cyte translated as 'cell' in modern usage) in academia and medical publishing, also known as red cells, [1] erythroid cells, and rarely haematids, are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O 2) to the body tissues—via ...
Micrograph showing nucleated red blood cells (bottom left of image), one of the elements necessary to call extramedullary hematopoiesis, in an endometrial polyp. H&E stain. Extramedullary hematopoiesis (EMH or sometimes EH [1]) refers to hematopoiesis occurring outside of the medulla of the bone (bone marrow). [2] It can be physiologic or ...
Human blood after separation by centrifugation. Plasma (upper layer), buffy coat (middle, white-colored layer) and erythrocyte (red blood cell) layer (bottom) can be seen. The buffy coat is commonly used for DNA extraction, [4] with leukocytes providing approximately 10 times more concentrated sources of nucleated cells. [5]
A proerythroblast (or rubriblast, or pronormoblast) is a precursor cell to the normoblast (nucleated red blood cell), as the earliest of four stages in its development. In histology, it is very difficult to distinguish it from the other "-blast" cells (lymphoblast, myeloblast, monoblast, and megakaryoblast).
There are four types of granulocytes (full name polymorphonuclear granulocytes): [3] Basophils; Eosinophils; Neutrophils; Mast cells; Except for the mast cells, their names are derived from their staining characteristics; for example, the most abundant granulocyte is the neutrophil granulocyte, which has neutrally staining cytoplasmic granules.
A marked increase of dacrocytes is known as dacrocytosis. These tear drop cells are found primarily in diseases with bone marrow fibrosis, such as: primary myelofibrosis, myelodysplastic syndromes during the late course of the disease, rare form of acute leukemias and myelophthisis caused by metastatic cancers.