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The prescribing of hypertonic IV therapy decreased the mortality rate of cholera to 40%, from 70%. In the West, IV therapy became the "gold standard" for the treatment of moderate and severe dehydration. [43] In 1953, Hemendra Nath Chatterjee published in The Lancet the results of using ORT to treat people with mild cholera. [44]
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Dehydration can occur as a result of diarrhea, vomiting, water scarcity, physical activity, and alcohol consumption. Management of dehydration (or rehydration) seeks to reverse dehydration by replenishing the lost water and electrolytes. Water and electrolytes can be given through a number of routes, including oral, intravenous, and rectal.
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Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.The intravenous route of administration is commonly used for rehydration or to provide nutrients for those who cannot, or will not—due to reduced mental states or otherwise—consume food or water by mouth.
Serum osmolarity above 295 mOsm/kg is typically seen in dehydration due to free water loss. [11] A urinalysis, which is a test that performs chemical and microscopic analysis of urine, may find darker color or foul odor with severe dehydration. [ 31 ]
Hypovolemia, also known as volume depletion or volume contraction, is a state of abnormally low extracellular fluid in the body. [1] This may be due to either a loss of both salt and water or a decrease in blood volume.