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Vitamin D compounds, specifically cholecalciferol (D3) and ergocalciferol (D2), are used in rodenticides due to their ability to induce hypercalcemia, a condition characterized by elevated calcium levels in the blood. This overdose leads to organ failure and is pharmacologically similar to vitamin D's toxic effects in humans.
The Institute of Medicine in 2010 recommended a maximum uptake of vitamin D of 4000 IU/d, finding that the dose for lowest observed adverse effect level is 40,000 IU daily for at least 12 weeks, [25] and that there was a single case of toxicity above 10 000 IU after more than seven years of daily intake; this case of toxicity occurred in ...
While some studies have found that vitamin D 3 raises 25(OH)D blood levels faster and remains active in the body longer, [43] [44] others contend that vitamin D 2 sources are equally bioavailable and effective for raising and sustaining 25(OH)D. [45] [46] If digestive disorders compromise absorption, then intramuscular injection of up to ...
Ergocalciferol, also known as vitamin D 2 and nonspecifically calciferol, is a type of vitamin D found in food. It is used as a dietary supplement [3] to prevent and treat vitamin D deficiency [4] due to poor absorption by the intestines or liver disease. [5]
It is used to prevent and treat lack of calcium and vitamin D in the elderly, as well for osteoporosis in combination with other medications. [ 1 ] [ 2 ] In 2022, the combination, calcium/vitamin D was the 246th most commonly prescribed medication in the United States, with more than 1 million prescriptions.
That includes antioxidants like vitamin C to protect against free radical damage, peptides and growth factors to strengthen and firm the skin, and hydrating ingredients such as hyaluronic acid and ...
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