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Based on risk assessment, a safe upper intake level of 250 μg (10,000 IU) per day in healthy adults has been suggested by non-government authors. [ 7 ] [ 8 ] Blood levels of 25-hydroxyvitamin D necessary to cause adverse effects in adults are thought to be greater than about 150 ng/mL, leading the Endocrine Society to suggest an upper limit ...
Specifically, consuming 2,000 IU (international units) a day of supplemental vitamin D3 without calcium over the course of more than five years did not reduce total fractures, hip, wrist or pelvic ...
$9.95 at Amazon. Vitamin Code Raw D3. This once-daily formula contains 5,000 IU of fat-soluble vitamin D3. “What I love about Garden of Life is that it also has probiotics mixed in, so you get a ...
Doses greater than 40 000 IU (1000 μg) per day are generally required before high blood calcium occurs. [12] Normal doses, 800–2000 IU per day, are safe in pregnancy. [5] Cholecalciferol was first described in 1936. [13] It is on the World Health Organization's List of Essential Medicines. [14]
The EFSA reviewed safe levels of intake in 2012, [168] setting the tolerable upper limit for adults at 100 μg/day (4000 IU), a similar conclusion as the IOM. The Swedish National Food Agency recommends a daily intake of 10 μg (400 IU) of vitamin D 3 for children and adults up to 75 years, and 20 μg (800 IU) for adults 75 and older.
In that study, the compliance calculation could be questionable since only random samples of the returned medications were counted. In a study by De Niet et al., [72] 60 subjects with vitamin D deficiency were randomized to receive 2000 IU vitamin D3 daily or 50 000 IU monthly. They reported a similar efficacy of the two dosing frequencies ...
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