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Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1] Tables of this general type are also available for NSAIDs, benzodiazepines, depressants, stimulants, anticholinergics and others.
Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...
The behavioral response to stimulants in children is similar regardless of whether they have ADHD or not. [38] Stimulant medication is an effective treatment [39] for adult attention-deficit hyperactivity disorder [40] [41] although the response rate may be lower for adults than children. [42]
Typically, the recommended starting dosage for Wellbutrin is 200mg per day, with a maximum dosage of 450mg per day. The starting dosage is taken as 100mg twice per day.
The conversion is rate-limited by the enzyme, which prevents high blood concentrations of dextroamphetamine and reduces lisdexamfetamine's drug liking and abuse potential at clinical doses. [ 236 ] [ 237 ] Vyvanse is marketed as once-a-day dosing as it provides a slow release of dextroamphetamine into the body.
The dosage may vary and is titrated to effect, with some guidelines recommending initial treatment with a low dose. [32] Methylphenidate is available in both immediate-release and extended-release (XR) formulations to provide a sustained release of the drug. [33] [34] Methylphenidate is not approved for children under six years of age. [35] [36]
Levoamphetamine [note 1] is a stimulant medication which is used in the treatment of certain medical conditions. [10] It was previously marketed by itself under the brand name Cydril, but is now available only in combination with dextroamphetamine in varying ratios under brand names like Adderall and Evekeo.
To avoid toxicity and risk of side effects, FDA guidelines recommend an initial dose of methamphetamine at doses 5–10 mg/day for ADHD in adults and children over six years of age, and may be increased at weekly intervals of 5 mg, up to 25 mg/day, until optimum clinical response is found; the usual effective dose is around 20–25 mg/day.