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As a seronegative spondyloarthropathy, laboratory analysis of blood will show that the patient is rheumatoid factor negative and often HLA-B27 positive. [7] The most common triggers are intestinal infections (with Salmonella , Shigella or Campylobacter ) and sexually transmitted infections (with Chlamydia trachomatis ); [ 8 ] however, it also ...
Fatigue can have significant negative impacts on quality of life. [156] Profound and debilitating fatigue is the most common complaint reported among individuals with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 diabetes, celiac disease, Myalgic Encephalomyelitis/chronic fatigue syndrome , and rheumatoid ...
Psychological symptoms are common in people with CHD, and while many psychological treatments may be offered following cardiac events, there is no evidence that they change mortality, the risk of revascularization procedures, or the rate of non-fatal myocardial infarction.
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
The symptoms do not lead to disablement and do not shorten life expectancy. [129] An 11-year follow-up study on 1,555 patients found that most remained with high levels of self-reported symptoms and distress. [non-primary source needed] [234] However, there was a great deal of patient heterogeneity accounting for almost half of the variance. At ...
Treatment is guided by the severity and specific cause of the disease. Treatment focuses on eliminating the underlying problem, whether that means discontinuing drugs suspected to cause it or treating underlying sepsis. Diagnosis and treatment of serious thrombocytopenia is usually directed by a hematologist.
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