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Remyelination is the process of propagating oligodendrocyte precursor cells to form oligodendrocytes to create new myelin sheaths on demyelinated axons in the Central nervous system (CNS). This is a process naturally regulated in the body and tends to be very efficient in a healthy CNS. [ 1 ]
A repair process, called remyelination, takes place in early phases of the disease, but the oligodendrocytes are unable to completely rebuild the cell's myelin sheath. Repeated attacks lead to successively less effective remyelinations, until a scar-like plaque is built up around the damaged axons.
The process and mechanistic function of myelinogenesis has traditionally been studied using ultrastructure and biochemical techniques in rat optic nerves. The implementation of this method of study has long allowed for experimental observation of myelinogenesis in a model organism nerve that consists entirely of unmyelinated axons. Furthermore ...
These markers are specific for the different processes that drive the formation of plaques: inflammation, myelin breakdown, astrogliosis, oligodendrocyte injury, neurodegeneration, axonal loss and remyelination. MS lesions evolve differently during early versus chronic disease phases, and within each phase, different kind of activity appears.
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The IRS said Friday it is sending a total of $2.4 billion in "special payments" to 1 million people, part of an effort to ensure that Americans who didn't receive all of their federal stimulus ...
On Dec. 6, the family received a phone call from immigration authorities and they were told to report to an office in Greenspoint, Texas, four days later to discuss Salazar-Hinojosa's case ...
10682 13595 Ensembl ENSG00000147155 ENSMUSG00000031168 UniProt Q15125 P70245 RefSeq (mRNA) NM_006579 NM_007898 RefSeq (protein) NP_006570 NP_031924 Location (UCSC) Chr X: 48.52 – 48.53 Mb Chr X: 8.05 – 8.06 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Emopamil binding protein is a protein that in humans is encoded by the EBP gene, located on the X chromosome. The protein is ...